Downstream Processing


Downstream Processing

Capabilities
  • Development of bench-scale processes for purification of recombinant proteins from E coli / yeast / mammalian systems.
  • Use of tangential flow filtration (TFF), ultrafiltration (hollow fiber system), affinity, ion exchange, hydrophobic interaction and reverse phase chromatography
  • Development of novel refolding methods of recombinant proteins from inclusion bodies for higher recovery.
  • Scale-up of protein purification processes to 2L/5L
Infrastructure
  • Low pressure and High pressure Chromatographic systems for protein purification
  • TFF system
  • High pressure Cell Disrupter.
  • 2D-Electrophoresis.





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