Capabilities

• Development of bench-scale processes for purification of recombinant proteins from E coli / yeast / mammalian systems.
• Use of tangential flow filtration (TFF), ultrafiltration (hollow fiber system), affinity, ion exchange, hydrophobic interaction and reverse phase chromatography.
• Development of novel refolding methods of recombinant proteins from inclusion bodies for higher refolding recovery.
• Scale-up of protein purification processes to 2L/5L.

Infrastructure

• Low pressure and High pressure Chromatographic systems for protein purification.
• TFF system.
• High pressure Cell Disrupter.
• 2D-Electrophoresis.