| INGREDIENTS
Eptifibatide injection is a clear, colorless, sterile, non-pyrogenic
solution for intravenous (IV) use. Each 10 ml vial contains 2 mg/ml
of Eptifibatide and each 100 ml vial contains 0.75 mg/ml of Eptifibatide.
CATEGORY
Glycoprotein IIb/IIIa receptor ( GP IIb/IIIa ) antagonist, antiplatelet.
INDICATIONS
Acute Coronary Syndrome
An IV bolus of 180 µg/kg as soon as possible following diagnosis,
followed by a continuous infusion of 2.0 µg/kg/min until hospital
discharge or initiation of CABG surgery, up to 72 hours. If a patient
is to undergo a percutaneous coronary intervention (PCI) while receiving
Eptifibatide, the infusion should be continued up to hospital discharge,
or for up to 18-24 hours after the procedure, whichever comes first,
allowing for up to 96 hours of therapy.
Percutaneous Coronary Intervention (PCI)
An IV bolus of 180 µg/kg administered immediately before the
initiation of PCI followed by a continuous infusion of 2.0 µg/kg/min
and a second 180 µg/kg bolus 10 minutes after the first bolus.
Infusion should be continued until hospital discharge, or for up
to 18-24 hours, whichever comes first. A minimum of 12 hours of
infusion is recommended.
In patients who undergo coronary artery bypass graft surgery, Eptifibatide
infusion should be discontinued prior to surgery.
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